Recombinant Human MEK1 (N-GST tag)


Recombinant Human MEK1 (N-GST tag)

Cat No.:HR2R1714
Product available

  Product info

Quantity: 10 μg

Gene Symbol: MEK1
Product Details

Gene ID N/A
Accession NM_002755
Alternative NameMAP2K1, MKK1, MAPKK1, PRKMK1
SpeciesHuman
SourceInsect cells
Description MEK1 is a member of the dual specificity protein kinase family that acts as a mitogen-activated protein kinase (MAPK) kinase. MEK1 lies upstream of MAPK/ERK and stimulates the enzymatic activity of MAPK/ERK upon a wide variety of extra- and intracellular signals. As an essential component of MAPK/ERK signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development . Constitutive activation of MEK1 results in cellular transformation. Thus, MEK1 represents a likely target for pharmacologic intervention in proliferative disease such as cancer .
Accession NM_002755
Functions The specific activity of MEK1 was determined to be 325 nmol /min/mg as per activity assay protocol.
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight72
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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