| Gene ID | 388372 |
| Accession | Q8NHW4 |
| Alternative Name | C-C motif chemokine 4-like, G-26, T-lymphocyte-secreted protein HC21, Lymphocyte activation gene 1 protein, LAG-1, MIP-1-beta, PAT 744, Protein H400, SIS-gamma, Small-inducible cytokine A4, T-cell activation protein 2, ACT-2, MIP1B, SCYA4<br/>Recombinant Human Lymphocyte Activation Gene-1 (CCL4L1) |
| Species | Human |
| Source | E. coli |
| Description | MIP-1-beta is one of the peptides of Macrophage Inflammatory Protein-1 that is produced by macrophages following their stimulation with bacterial endotoxins. MIP-1-beta causes local inflammatory responses, and induces superoxide production by neutrophils. The aforementioned activates of MIP-1-beta are exerted following its binding to CCR5. |
| Accession | Q8NHW4 |
| Functions | Determined by its ability to chemoattract human blood monocytes using a concentration range of 2-10 ng/mL. |
| Formulation | Lyophilized from a 0.2 ?m filtered PBS solution |
| Solubility | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Appearance | Lyophilized Powder |
| Molecular Weight | 8.1 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | <1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Shipping Condition | Ambient Temperature |
| Storage Condition | The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |