| Gene ID | 6363 |
| Accession | Q99731 |
| Alternative Name | MIP-3-beta, C-C motif chemokine 19, MIP3, Beta-chemokine exodus-3, CK beta-11, Epstein-Barr virus-induced molecule 1 ligand chemokine, EBI1 ligand chemokine, ELC, Small-inducible cytokine A19, Exodus-3<br/>Recombinant Human Macrophage Inflammatory Protein-3 Beta (CCL19) |
| Species | Human |
| Source | E. coli |
| Description | CCL19 is a chemokine that belongs to the CC family of growth factors and signals through the CCR7 receptor. CCl19 has been shown to be expressed in the thymus, lymph nodes and in activated bone marrow stromal cells. When anti-inflammatory signals are released, expression of CCL19 gets down-regulated ? specifically by IL-10. |
| Accession | Q99731 |
| Functions | Measured by its ability to chemoattract 5 ? 10 day cultured human peripheral blood lymphocytes (PBL). The ED(50) for this effect is typically 0.1?0.3 μg/mL. |
| Formulation | Lyophilized from a 0.2 ?m filtered solution in Acetonitrile and TFA with BSA as a carrier protein |
| Solubility | Reconstitute at 25 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin |
| Appearance | Lyophilized Powder |
| Molecular Weight | 9.1 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | <1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Shipping Condition | Ambient Temperature |
| Storage Condition | The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |