Recombinant Human MLK4 (N-GST tag)


Recombinant Human MLK4 (N-GST tag)

Cat No.:HR2R1755
Product available

  Product info

Quantity: 10 μg

Gene Symbol: MLK4
Product Details

Gene ID N/A
Accession NM_032435
Alternative NamedJ862P8.3; KIAA1804; RP5-862P8.2
SpeciesHuman
SourceInsect cells
Description MLK4 or mixed lineage kinase 4 belongs to the superfamily of MAP kinase kinase kinases (MAP3K1) which contain both ser/thr and tyr kinases activity in their catalytic domains. The structure of this kinase family incorporates an N-terminal Src homology (SH3) domain, followed by the kinase domain, a leucine zipper region, and a CDC42 /RAC -interactive binding (CRIB) motif, but divergent C-terminal regions. MLK4 is highly expressed in kidney and pancreas . MLK4 is a negative regulator of TLR4 .
Accession NM_032435
Functions The specific activity of MLK4 was determined to be 22nmol /min/mg as per activity assay protocol.
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight61
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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