Gene ID | N/A |
Accession | NM_003607 |
Alternative Name | CDC42BPA, MRCK, PK428, FLJ23347, KIAA0451, DKFZp686L1738, DKFZp686P1738 |
Species | Human |
Source | Insect cells |
Description | Myotonic Dystrophy Kinase-Related Cdc42-Binding Kinase a (MRCKa) is a Cdc42/Rac/Rho interactive/binding serine/threonine kinase with multiple functional domains . MRCK are effectors of RhoA and Cdc42, respectively, for actin reorganization. MRCKa is a critical regulator of signal transduction pathways in eukaryotic cells that are known principally for their role in regulating the cytoskeleton, and they do so by recruiting a variety of downstream effector proteins . |
Accession | NM_003607 |
Functions | The specific activity of MRCKa was determined to be 101 nmol /min/mg as per activity assay protocol. |
Formulation | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. |
Solubility | N/A |
Appearance | Liquid |
Molecular Weight | 73 |
Purity | 70% - 90% |
Shipping Condition | Dry Ice |
Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |