Recombinant Human MYO3alpha (N-GST tag)


Recombinant Human MYO3alpha (N-GST tag)

Cat No.:HR2R1776
Product available

  Product info

Quantity: 10 μg

Gene Symbol: MYO3a
Product Details

Gene ID N/A
Accession NM_017433
Alternative Namemyosin IIIA; DFNB30
SpeciesHuman
SourceInsect cells
Description MYO3alpha belongs to the myosin superfamily which are members of the large myosin superfamily and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as MYO3alpha, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors . MYO3alpha plays an important role in hearing in humans and mutations in the MYO3alpha have been shown to cause nonsyndromic progressive hearing loss . MYO3alpha is highly expreesed in retina and cochlea.
Accession NM_017433
Functions The specific activity of MYO3awas determined to be 4 nmol /min/mg as per activity assay protocol.
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight76
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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