Recombinant Human NEK5 (N-GST tag)


Recombinant Human NEK5 (N-GST tag)

Cat No.:HR2R1785
Product available

  Product info

Quantity: 10 μg

Gene Symbol: NEK5
Product Details

Gene ID N/A
Accession NM_199289
Alternative NameMGC75495
SpeciesHuman
SourceInsect cells
Description NEK5 or NIMA (never in mitosis gene a)-related kinase 5 is a serine/threonine kinase that is involved in cell cycle regulation. NEK5 has been shown to interact with NEK6 and NEK5 are required for the ibo1/nek6 ectopic outgrowth phenotype in epidermal cells . NEK6 interacts and co-localizes with NEK5 in a transient expression assay. The ibo1-3 mutation markedly increases the interaction between NEK6 and NEK5. NEK6 forms heterodimers with NEK5 to regulate cortical microtubule organization possibly through the phosphorylation of ?-tubulins. The NEK5 gene is conserved in chimpanzee, cow, mouse, rat, and chicken.
Accession NM_199289
Functions The specific activity of NEK5 was determined to be 100 nmol /min/mg as per activity assay protocol.
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight84
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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