| Gene ID | N/A |
| Accession | BC011526, NM_145012 |
| Alternative Name | PCTK3: PCTAIRE, PCTAIRE3 CyclinY: CCNY; C10orf9; CBCP1; CCNX; CFP1 |
| Species | Human |
| Source | Insect cells |
| Description | PCTK3 or PCTAIRE protein kinase 3 is a member of the cdc2/cdkx subfamily of the ser/thr family of protein kinases. PCTK3 is thought to play a role in terminally differentiated neurons and it contains an N-terminal extension relative to CDC2 . PCTK3 is expressed in a variety of human cell lines and tissues . Elevation in the protein levels of PCTAIRE 3 in the temporal cortex of Alzheimer's disease relative to control brains, have been observed. It is proposed that PCTAIRE 3 is a paired helical filaments-associated kinase that modulates tau phosphorylation. |
| Accession | BC011526, NM_145012 |
| Functions | The specific activity of PCTK3 (CDK18)/CyclinY was determined to be 46 nmol /min/mg as per activity assay protocol. |
| Formulation | 50mM Tris-HCl, , pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Solubility | N/A |
| Appearance | Liquid |
| Molecular Weight | 76 |
| Purity | 70% - 90% |
| Shipping Condition | Dry Ice |
| Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |