Recombinant Human PKAc alpha (N-GST tag)


Recombinant Human PKAc alpha (N-GST tag)

Cat No.:HR2R1869
Product available

  Product info

Quantity: 10 μg

Gene Symbol: PKAca
Product Details

Gene ID N/A
Accession NM_002730
Alternative NamePKAa; cAPKa; MGC48865; MGC102831
SpeciesHuman
SourceInsect cells
Description The catalytic subunit C-alpha of PKA (PKAca) is a member of the Ser/Thr protein kinase family and has been assigned to chromosome region 19p13.1 . Null mutation in PKAca leads to early postnatal lethality in the majority of C-alpha knockout mice. Surprisingly, a small percentage of C-alpha knockout mice, although runted, survived to adulthood. In these animals, compensatory increases in C-beta levels occurred in brain whereas many tissues, including skeletal muscle, heart, and sperm, contained less than 10% of the normal PKA activity .
Accession NM_002730
Functions The specific activity of PKAca was determined to be 1665 nmol/min/mg as per activity assay protocol.
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight69
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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