Gene ID | N/A |
Accession | NM_005400 |
Alternative Name | PRKCE; MGC125656; MGC125657; nPKC-epsilon |
Species | Human |
Source | Insect cells |
Description | PKCe is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. PKCe is involved in many different cellular functions, such as neuron channel activation , cardioprotection from ischemia , heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may control anxiety-like behavior . |
Accession | NM_005400 |
Functions | The specific activity of PKCe was determined to be 1258 nmol /min/mg as per activity assay protocol |
Formulation | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Solubility | N/A |
Appearance | Liquid |
Molecular Weight | 110 |
Purity | 70% - 90% |
Shipping Condition | Dry Ice |
Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |