Recombinant Human PKC zeta (N-GST tag)


Recombinant Human PKC zeta (N-GST tag)

Cat No.:HR2R1883
Product available

  Product info

Quantity: 10 μg

Gene Symbol: PKC?
Product Details

Gene ID N/A
Accession NM_002744
Alternative NamePRKCZ; PRKCZ; PKC2
SpeciesHuman
SourceInsect cells
Description PKC? is an atypical isoform of the PKC family. PKC? is found in both particulate and soluble fractions and cannot be activated by phorbol ester. Overexpression of PKC? and subsequent phorbol ester treatment abolished phorbol ester-induced reduction in cell proliferation . Overexpression of PKC? also potentiates phorbol ester-induced mitogen-activated protein (MAP) kinase activation in a PKC-dependent manner. PKC? is an upstream modulator of p70S6K, an important regulator of cell proliferation .?
Accession NM_002744
Functions The specific activity of PKC? was determined to be 130 nmol /min/mg as per activity assay protocol
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Solubility N/A
Appearance Liquid
Molecular Weight93
Purity70% - 90%
Shipping ConditionDry Ice
Storage Condition Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

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