Gene ID | N/A |
Accession | NM_004073 |
Alternative Name | CNK, FNK, PRK |
Species | Human |
Source | Insect cells |
Description | PLK3 or Polo-like kinase 3 is a cytokine-inducible kinase that is a member of the Polo family of serine/threonine protein kinases. PLK3 contains both a catalytic domain and a putative regulatory domain and plays an important role in the regulation of cell cycle progression and tumorigenesis . PLK3 is closely associated with centrosomes in several human cell lines and its localization is dependent on the integrity of microtubules. Hence, PLK3 is also involved in regulating microtubule dynamics and centrosomal function . |
Accession | NM_004073 |
Functions | The specific activity of PLK3 was determined to be 2.2 nmol /min/mg as per activity assay protocol. |
Formulation | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Solubility | N/A |
Appearance | Liquid |
Molecular Weight | 60 |
Purity | 70% - 90% |
Shipping Condition | Dry Ice |
Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |