| Gene ID | N/A |
| Accession | NM_015375 |
| Alternative Name | DSTYK; DustyPK; HDCMD38P; KIAA0472; RIP5 |
| Species | Human |
| Source | Insect cells |
| Description | ?RIPK5 is a dual specificity serine/threonine and tyrosine protein kinase that is a member of the RIPK family. RIPK5 is widely expressed in vertebrates with broad distributed in the central nervous system, and deregulated in certain human cancers . RIPK5 has been shown to function as a regulator of cell death. Overexpression of RIPK5 leads to cell death as evidenced by DNA fragmentation . RIPK5 induces both caspase-dependent and caspase-independent cell death, and N- and C-terminal RIPK5 deletion mutants retained the ability to induce cell death. |
| Accession | NM_015375 |
| Functions | The specific activity of RIPK5 was determined to be 6 nmol /min/mg as per activity assay protocol |
| Formulation | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Solubility | N/A |
| Appearance | Liquid |
| Molecular Weight | 140 |
| Purity | 70% - 90% |
| Shipping Condition | Dry Ice |
| Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |