| Gene ID | 6361 |
| Accession | Q92583 |
| Alternative Name | CC chemokine TARC, Small-inducible cytokine A17, C-C motif chemokine 17, chemokine 17, CCL17, ABCD-2, SCYA17, TARC<br/>Recombinant Human Thymus and Activation-Regulated Chemokine (CCL17) |
| Species | Human |
| Source | E. coli |
| Description | Thymus and activation-regulated chemokine (TARC) is a recently identified CC chemokine that is expressed constitutively in the thymus and transiently in stimulated peripheral blood mononuclear cells. TARC functions as a selective chemoattractant for T cells that express a class of receptors binding TARC with high affinity and specificity. The chemokine TARC is a ligand for the chemokine receptor CCR4 expressed on CD4 Th2 cells. |
| Accession | Q92583 |
| Functions | Determined by its ability to chemoattract human T cells using a concentration range of 2-40 ng/mL. |
| Formulation | Recombinant TARC was lyophilized from a 0.2 ?m filtered 20 mM PB,100 mM NaCl solution pH 7.5. |
| Solubility | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Appearance | Lyophilized Powder |
| Molecular Weight | 8 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | <1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Shipping Condition | Ambient Temperature |
| Storage Condition | The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |