| Gene ID |
7423 |
| Accession | P49765 |
| Alternative Name | VEGF-related factor |
| Species | Human |
| Source | E. coli |
| Description | Vascular endothelial growth factor B (VEGFB) is a homodimeric, heparin-binding glycoprotein member of the VEGF family of growth factors. Compared to VEGFA, VEGFB?s main role is the maintenance of newly formed blood vessels and is involved in endothelial cell physiology. It is a ligand for vascular endothelial growth factor receptor 1 (VEGFR1) and neuropilin-1 (NRP1), while the binding of neuropilin-1 to VEGFB186 is proteolysis regulated. |
| Accession | P49765 |
| Functions | Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast. The ED50 for this effect is < 1ng/ml. |
| Formulation | Lyophilized as a 0.2 ?m filtered solution in Acetonitrile and TFA |
| Solubility | N/A |
| Appearance | Lyophilized Powder |
| Molecular Weight | 19 |
| Purity | >95% as determined by SDS-PAGE |
| Concentration | <1.0 EU/μg of recombinant protein as determined by the LAL method |
| Shipping Condition | Ambient Temperature |
| Storage Condition | The lyophilized protein is stable for at least one year from date of receipt at -70?C. Upon reconstitution, this cytokine can be stored in working aliquots at 2? - 8?C for one month, or at -20?C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles. |
