| Gene ID |
N/A |
| Accession | NM_001721 |
| Alternative Name | Bone marrow tyrosine kinase, ETK, PSCTK2, PSCTK3 |
| Species | Human |
| Source | Insect Cells |
| Description | Recombinant full-length human BMX was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The BMX gene encodes a non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells. The BMX gene is located on chromosomal band Xp22.2 between the DXS197 and DXS207 loci. Interestingly, chromosome X also contains the closest relative of BMX, the BTK gene, implicated in X-linked agammaglobulinemia. BMX is found to induce activation of the Stat signalling pathway. |
| Accession | NM_001721 |
| Functions | The specific activity of BMX was determined to be 34 nmol/min/ml. |
| Formulation | Recombinant BMX is stored in 50 mM Tris-HCl (pH 7.5), 150 mM NaCl, 0.25 mM DTT, 10 mM glutathione, 0.1 mM EDTA, 0.1 mM PMSF, 25% Glycerol at 0.1 μg/?l. |
| Solubility | N/A |
| Appearance | Liquid |
| Molecular Weight | 110 |
| Purity | >80% as determined by SDS-PAGE |
| Shipping Condition | Dry Ice |
| Storage Condition | Store product at ?70?C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
